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Chronic renal failure is a clinical syndrome consisting of a variety of symptoms and metabolic disorders due to the progressive irreversible decline of the kidney functions. The end stage of chronic renal failure is uremia. Uremia is not an independent kidney disease, but a series of clinical manifestations and it is the common syndrome of nearly all the kidney diseases in their end stages. In the end stage of uremia, nearly all the systems will be involved. The patients will have some severe illness conditions such as heart failure, psychosis, coma and other life-threatening complications.