Wegener's granulomatosis (WG), now officially known as granulomatosis with polyangiitis (GPA), is a form of vasculitis (inflammation of blood vessels) that affects small- and medium-size vessels in many organs. Damage to the lungs and kidneys can be fatal. It requires long-term immunosuppression. Five-year survival is up to 87%, with some of the mortality due to toxicity of treatment. It is named after Friedrich Wegener, who described the disease in 1936. Because of Wegener's Nazi past, professional bodies and journals have replaced his name with a descriptive name.